Epidermodysplasia Verruciformis, Wart, Flat, Wart, Verruca - DermAtlas

Contributor

Lauren Hammock, MD

Diagnosis

epidermodysplasia verruciformis wart, flat wart verruca

Body Site

arm

Age

13 years

Pigmentation

dark

Organization

grouped, clustered linear

Color

white/hypo

Morphology

papulosquamous (bump, scale)

Pattern

generalized, disseminated

Comments

These changes have also been reported in widely disseminated flat warts in some patients with Human Immunodeficiency Virus infection.

Description

Histologic sections of skin demonstrate a verruciform epidermis. Higher magnification of the epidermis reveals that some of the keratinocytes are arranged in a vaguely nested pattern in the upper spinous and granular layers. The ample and distinctively steel-gray cytoplasm seen in these keratinocytes is a specific viral cytopathic effect often observed in epidermodysplasia verruciformis.

Image Added

8/20/2004 18:10:47

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Other Resources

PubMed Medline Plus Medscape

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