This healthy 8-year-old boy developed crusted erosions on his lips, erosions on his palate and buccal mucosa, and discrete and confluent red papules some with central bullae on his upper chest and distal extremities including the palms and soles. His eyes were clear. He was admitted to the hospital for rehydration, because he was unable to eat of drink. He was treated with oral steroid, and was discharged 3 days later with good oral intake and decreased oral pain. He had clinical features overlapping Stevens-Johnson syndrome and erythema multiforme (classic Von Hebra type). The lack of conjunctival involvement is unusual for Stevens-Johnson syndrome, but the involvement of the mouth, trunk, and extremities was more typical. The involvement of the distal extremities and the presence of target lesions on the dorsum and ventral surfaces of his hands and feet is typical of erythema multiforme.