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Contributor

Vincent C.B. Lin, MD

Diagnosis

acute generalized exanthematous pustulosis drug reaction, pustular

Body Site

total body forearm

Age

46 years

Pigmentation

medium

Organization

confluent discrete

Color

red

Morphology

edema

Pattern

generalized, disseminated

Comments

This 46-year-oldl woman developed generalized erythema, most severe on the proximal extremities and trunk, several hours after receiving parenteral normal saline with iron, amino acids, and cobalamin at a medical clinic. Numerous confluent pustules superimposed on the erythematous edematous confluent plaques followed one day later. Although she was afebrile, leukocytosis(18,000/cubic mm) and elevated CRP were noted. A bacterial culture from the pustules was negative. A skin biopsy showed intracorneal pustules with numerous neutrophils and neutrophilc infiltration of the epidermis and upper dermis.

Description

generalized erythema and edema with superimposed discrete and confluent 2-3 mm pustules

Categories

drug reaction

Image Added

11/27/2005 17:46:27

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PubMed Medline Plus Medscape

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