Advanced Search
Search
Diagnosis
Pigmentation
Color
Body Site
Age
Author
Morphology
Pattern
Organization
Category
Close
Search

Contributor

Bernard Cohen, MD

Diagnosis

lupus erythematosus connective tissue disease, mixed

Body Site

hand knuckle

Age

14 years

Pigmentation

medium

Organization

grouped, clustered

Color

white/hypo red

Morphology

fibrosis (scar, increased collagen)

Pattern

symmetric acral (centripetal - extremity predominant)

Comments

This healthy adolescent had a 1 year history of fatigue, intermittent fevers, myalgias, and joint pain and swelling associated with atrophic hypopigmented papules over her knuckles. A skin biopsy of a lesion on a knuckle and a subcutaneous nodule on her right forearm showed dermal mucinosis with overlying fibrosis and atrophy and telangiectasias but no evidence of vacuolar change. She also had mild narrowing of the distal fingers but no history of Raunaud phenomenon. Her clinical and histologic findings were consistent with features of several overlapping connective tissue disorders. Her joint symptoms and fatigue resolved with systemic steroids. An extensive laboratory evaluation was pending.

Description

atrophic hypopigmented plaques with surrounding telangiectasias

Categories

collagen vascular disease atrophy

Image Added

11/30/2003 19:05:44

Translate

Other Resources

PubMed Medline Plus Medscape

Image Options

Share