Leishmaniasis - DermAtlas - Dermatology Image Atlas

Contributor

Greg Hosler, MD, PhD

Diagnosis

leishmaniasis

Body Site

abdomen

Age

64 years

Pigmentation

medium

Organization

discrete

Color

red brown

Morphology

papule

Pattern

solitary

Comments

Cutaneous leishmaniasis is unsual in the United States. However, we have a few cases every year around Denton, TX. The sandfly is the vector and the organism is usually L. braziliensis. The organism packs macrophages giving them a bubbly cytoplasm. The histologic differential diagnosis includes histoplasmosis and toxoplasmosis among others. Leishmaniasis can be diagnosed on H&E sections if one appreciates the kinetoplast. Otherwise a Giemsa stain may be helpful.

Description

Within the dermis, there is a heavy, mixed inflammatory infiltrate. Numerous "punched-out" appearing holes are present. The epidermis is ulcerated (not this section).

Image Added

11/25/2006 16:37:21

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PubMed Medline Plus Medscape

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