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Contributor

Greg Hosler, MD, PhD

Diagnosis

lichen amyloidosis

Body Site

shin

Age

25 years

Pigmentation

medium

Organization

extensor surfaces

Color

brown

Morphology

papule

Pattern

localized

Comments

This biopsy from a 25 year old woman was submitted to rule out hypertrophic lichen planus. She had hyperkeratotic and almost verrucous plaques on her shins. They were pruritic. This biopsy has a low power look of lichen simplex chronicus, which is a typical finding in lichen amyloidosis. The amyloid collects in the dermal papillae and consists of keratins. It is likely related to LSC as both are associated with chronic rubbing.

Description

The eosinophilic amorphous material, or amyloid, collects in the dermal papillae, accentuated around vessels. It is acellular. The overlying epidermis is acanthotic.

Categories

deposition disorders papulosquamous eruptions

Image Added

5/6/2009 22:01:06

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Other Resources

PubMed Medline Plus Medscape

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