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Contributor

Roberson Ramos, MD

Diagnosis

fungal infection, deep Lobo disease (Jorge) lobomycosis keloidal blastomycosis

Body Site

arm shoulder

Age

14 years

Pigmentation

medium

Organization

grouped, clustered

Color

skin color brown

Morphology

nodule

Pattern

asymmetric

Comments

A 14-year-old girl developed 2 firm nodules at the site of a previous BCG vaccination. A skin biopsy revealed fungal structures typical of Loboa loboi, the agent responsible for Lobomycosis also known as keloidal blastomycosis. This deep fungal infection is characterized by slow growing keloid-like nodules or ulcerated verrucous plaques on exposed body sites. This infection is found almost exclusively in Central and South America. It affects humans and dolphins, and squamous cell carcinoma has been described as a rare complication in chronic lesions. Histopathology demonstrates extensive granulomatous inflammation, and fungal cells are readily identified both inside and outside of macrophages.

Description

1 cm and 2 cm dome shaped firm smooth topped nodules

Categories

tropical medicine infections and infestations lumps & bumps (plaques, nodules, tumors)

Image Added

10/30/2004 12:42:28

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Other Resources

PubMed Medline Plus Medscape

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