Lymphoma, Anaplastic Large Cell, Lymphoma, T-cell, Lymphoma - DermAtlas

Contributor

Bernard Cohen, MD

Diagnosis

lymphoma, anaplastic large cell lymphoma, T-cell lymphoma

Body Site

scalp

Age

14 years

Pigmentation

dark

Organization

Color

Morphology

Pattern

Comments

These findings supported the diagnosis of a CD30+ lymphoproliferative disorder and in this patient anaplastic large cell lymphoma.

Description

Immunohistochemical stains demonstrate that the atypical mononuclear cell infiltrate is composed of CD3+ T cells that co-express CD4. An immunostain for CD30 demonstrates diffuse positivity within the atypical population. The atypical cells are negative for CD15, EMA and ALK. Expression of CD7 is largely retained. The surrounding inflammatory infiltrate shows scattered CD8+ T cells which are small and lack cytologic atypia.

Image Added

1/13/2008 16:38:34

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PubMed Medline Plus Medscape

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