Hyperpigmentation, Drug Reaction, Hyperpigmentation, Minocycline Reaction - DermAtlas

Contributor

Bernard Cohen, MD

Diagnosis

hyperpigmentation drug reaction, hyperpigmentation minocycline reaction

Body Site

leg shin

Age

54 years

Pigmentation

light

Organization

patchy

Color

brown bronze

Morphology

macular / flat (macule / patch)

Pattern

asymmetric

Comments

This 54-year-old man with a history of recurrent acne was treated intermittently with oral minocycline. He developed subtle generalized hyperpigmentation and patchy bronze-brown patches on his left leg. He had chronic edema and a well healed scar on the left leg from an old injury. A skin biopsy showed increased melanin and hemosiderin-like pigment consistent with the melanin-iron complex found in some patients with minocycline hyperpigmentation.

Description

subtle generalized hyperpigmentation and irregular patchy bronze-brown hyperpigmentation around scar

Image Added

10/30/2004 18:57:39

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Other Resources

PubMed Medline Plus Medscape

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