Neurofibroma - DermAtlas - Dermatology Image Atlas

Contributor

Greg Hosler, MD, PhD

Diagnosis

neurofibroma

Body Site

chest

Age

74 years

Pigmentation

light

Organization

discrete

Color

pink

Morphology

papule

Pattern

solitary

Comments

This is a very typical example of a common lesion. The histologic differential diagnosis includes a neuritized nevus and perhaps other soft tissue tumors such as a dermatofibroma or neuroma. The lesion contains a mixture of axons, mast cells, and nerve sheath cells (fibroblasts and Schwann cells). These will stain positive for S-100 and neurofilament (scattered twigs) if needed.

Description

There is a fairly well-demarcated but unencapsulated spindle cell tumor within the dremis. The epidermis is uninvolved. The spindle cells are monomorphic and imperceptibly blend into the surrounding dermis. The lesion is slightly more pink than the dermal collagen.

Image Added

5/17/2007 18:03:16

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PubMed Medline Plus Medscape

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