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Contributor

Bernard Cohen, MD

Diagnosis

pemphigus vulgaris

Body Site

chest abdomen

Age

9 years

Pigmentation

light

Organization

reticulated annular

Color

red

Morphology

ulcerated (erosion / ulcer)

Pattern

symmetric generalized, disseminated

Comments

This 9 year old boy developed a generalized recalcitrant vesiculobullous eruption with involvement of the oral pharynx, nasal pharynx, larynx, conjunctivae, and perianal skin. He failed to stay in remission with oral and parenteral steroids, methotrexate, and dapsone. He eventually cleared on plasmaphoresis and pulse parenteral cyclophosphamide give in conjuction with a 6 month tapering course of oral steroids, and a year of oral cytoxan.

Description

generalized vesicles and bullae with many on the border of annular eroded plaques

Categories

vesiculobullous eruptions vesiculobullous eruptions, immunobullous

Image Added

5/14/2002 23:49:16

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PubMed Medline Plus Medscape

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