Vasculitis, Leukocytoclastic - DermAtlas

Contributor

Alison Young, MD

Diagnosis

vasculitis, leukocytoclastic

Body Site

leg thigh

Age

32 weeks

Pigmentation

light

Organization

confluent

Color

purple

Morphology

papulosquamous (bump, scale)

Pattern

symmetric

Comments

Direct immunofluorescence of the skin biopsy showed IgA, IgG, IgM and complement deposition rather than selective IgA deposition typical of Henoch Schonlein purpura. Renal biopsy showed crescenteric glomerulonephritis, with absence of IgA deposition. These changes are consistent with the small vessel vasculitis seen in post streptococcal disease.

Description

Neutrophilic Infiltration of blood vessel walls, fibrinoid necrosis, and nuclear dust are seen in superficial dermal blood vessels.

Image Added

5/2/2004 21:00:14

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Other Resources

PubMed Medline Plus Medscape

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