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Contributor

Shimizu Tominaga, MD, PhD

Diagnosis

SAPHO(synovitis, acne, pustulosis, hyperostosis, osteitis) syndrome

Body Site

palm sole foot

Age

45 years

Pigmentation

Organization

confluent

Color

red

Morphology

papulosquamous (bump, scale)

Pattern

acral (centripetal - extremity predominant) symmetric

Comments

A 37-year-old woman with a history of palmoplantar pustulosis presented with severe chest pain. The patient was first diagnosed with palmoplantar pustulosis at the age of 36 and soon afterwards suffered from upper chest pain. Although the pain and skin lesion had been relieved for three years after excision of the left first sternocostal articulation, she experienced subsequent relapse of sternal pain and palmoplantar pustulosis. Medication for rheumatoid arthritis, such as prednisolone, bucillamine, and methotrexate, or antibiotic therapy failed to ameliorate the symptoms. At the age of 45, she underwent palatine tonsillectomy with resolution of symptoms. At present, the patient has neither palmoplantar skin lesions nor sternal pain.

Description

symmetric thick scaly red acral plaques studded with pustules

Categories

cutaneous sign of systemic disease

Image Added

6/5/2005 11:27:32

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Other Resources

PubMed Medline Plus Medscape

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