Pyoderma Gangrenosum, Lupus Erythematosus, Systemic - DermAtlas

Contributor

Grant Anhalt, MD

Diagnosis

pyoderma gangrenosum lupus erythematosus, systemic

Body Site

leg ankle

Age

50 years

Pigmentation

light

Organization

Color

purple red

Morphology

ulcerated (erosion / ulcer)

Pattern

solitary

Comments

This 50-year-old woman with a history of systemic lupus erythematosus, antiphospholipid syndrome, and urticarial vasculitis developed an enlarging non-healing ulcer on her right ankle 10 months earlier. Multiple tissue cultures were negative, and she failed to respond to oral cyclosporine, plaquenil 200 mg twice daily, cellcept 3 grams/day, and oral prednisone 60 mg/day. Further evaluation failed to reveal infection, and the ulcer began to improve within several days of treatment with pulsed parenteral corticosteroids.

Description

chronic full thickness ulcer with necrotic borders and a new expanding undermined ulcer at the inferior margin

Image Added

5/10/2003 18:22:29

Translate

Other Resources

PubMed Medline Plus Medscape

Image Options

View Image in New Window