Toxic Epidermal Necrolysis, Stevens-Johnson Syndrome, Drug Reaction, Nikolsky Sign - DermAtlas

Contributor

Bernard Cohen, MD

Diagnosis

toxic epidermal necrolysis Stevens-Johnson syndrome drug reaction Nikolsky sign

Body Site

leg

Age

10 years

Pigmentation

dark

Organization

discrete

Color

purple

Morphology

vesiculobullous (blister, pustule)

Pattern

generalized, disseminated symmetric

Comments

This healthy 10-year-old boy had a seizure and was started on oral phenytoin. Three weeks later he developed conjunctivitis and oral mucositis. Within 48 hours he blossomed with confluent erosions above the waist and necrotic vesicles and bullae on the legs and feet.

Description

diffuse and confluent ulceration of skin and mucous membranes

Image Added

4/24/2006 22:50:47

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Other Resources

PubMed Medline Plus Medscape

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